Small Sample Research Designs for Evidence-Based Rehabilitation: Issues and Methods

Small N designs for rehabilitation research.

Rehabilitation research presents unique and challenging problems to investigators during both the design and analysis periods. Statistical issues regarding sample size requirements for an adequately powered study may be in direct conflict with realistic recruitment and subject retention goals. Issues of underpowered studies, sample size requirements, and recruitment goals plague rehabilitation ...

Small Sample Issues for Microarray-Based Classification

In order to study the molecular biological differences between normal and diseased tissues, it is desirable to perform classification among diseases and stages of disease using microarray-based gene-expression values. Owing to the limited number of microarrays typically used in these studies, serious issues arise with respect to the design, performance and analysis of classifiers based on micro...

Community-based Health Research: Issues and Methods

So many, 11 of 14, contributors to this volume are from the Atlanta area that I expected this book to speak with a Southern drawl. That it does not attests to how much this metropolis, growing in kudzu-fashion, has changed. This element of profound change is also a major motif in the 10 chapters collected by the editors to promote community-based health research as a mechanism for addressing hi...

Community-Based Health Research: Issues and Methods

Community-Based Health Research: Issues and Methods is an important text for future public health researchers. As the authors note, public health prevention has moved from treating infectious diseases to preventing chronic diseases such as diabetes and heart disease. This evolution argues that our approaches must change as well. The Blumenthal and DiClemente volume provides 3 key perspectives o...

Biostatistical Methods and Research Designs